Cow's milk may be an effective way of oral delivery of RNA drugs
Source: world-nan.kz
According to the Journal of Nanobiotechnology, scientists have announced the potential effectiveness of the smallest particles present in cow's milk as a method of oral delivery of RNA drugs.
Ribonucleic acid (RNA) therapy is a promising class of drugs offering a new way to combat previously incurable diseases at the molecular level. However, until now there has been no effective method of their oral delivery due to their destruction in harsh conditions of the digestive tract.
In a new study conducted by Dr. Driton Vllasaliou and colleagues from King's College London, it was found that extracellular vesicles (EVs), the smallest particles of cow's milk, can effectively protect and deliver RNA drugs after oral administration. These EVs are naturally absorbed in the intestine and can serve as a means of transferring biological molecules from mother to child.
Studies have shown that this method has been successfully used to treat inflammatory bowel diseases in both laboratory models of human intestines and mice. It is important to note that dairy drug delivery is considered safer because, unlike synthetic nanoparticles, it does not cause negative reactions from the immune system.
In a new study conducted by Dr. Driton Vllasaliou and colleagues from King's College London, it was found that extracellular vesicles (EVs), the smallest particles of cow's milk, can effectively protect and deliver RNA drugs after oral administration. These EVs are naturally absorbed in the intestine and can serve as a means of transferring biological molecules from mother to child.
Studies have shown that this method has been successfully used to treat inflammatory bowel diseases in both laboratory models of human intestines and mice. It is important to note that dairy drug delivery is considered safer because, unlike synthetic nanoparticles, it does not cause negative reactions from the immune system.
